Human IGF-I: How 70 Amino Acids Coordinate Growth, Metabolism and Survival
IGF-I is a 70-residue growth factor acting through IGF-1R to drive PI3K-AKT and MAPK signaling. This article explains how one small peptide coordinates three programs.
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Abstract: IGF-I is a 70-residue growth factor acting through IGF-1R to drive PI3K-AKT and MAPK signaling. This article explains how one small peptide coordinates three programs.
Keywords: IGF-I, IGF-1, IGF-1R, insulin-like growth factor, PI3K AKT, MAPK, growth factor, UA100025
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
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