GPC3: Molecular Mechanisms of Glypican-3 and the Landscape of HCC-Targeted Research

GPC3 is a member of the GPI-anchored heparan sulfate proteoglycan family. This review covers its molecular structure, the Xq26.2 gene locus, its developmental-adult-tumor expression profile, and the panorama of liver cancer targeted research.

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Abstract: GPC3 is a member of the GPI-anchored heparan sulfate proteoglycan family. This review covers its molecular structure, the Xq26.2 gene locus, its developmental-adult-tumor expression profile, and the panorama of liver cancer targeted research.

Keywords: GPC3, glypican-3, hepatocellular carcinoma, HCC targeted therapy, heparan sulfate proteoglycan, UA016106

Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.

This article is reviewed and published by the technical expert team of UA

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