Three Keys, One Lock: How IL-2 Assembles Its Ternary Receptor Complex
IL-2 activates T cells like opening a triple lock: first captured by IL-2R alpha (CD25), then completed into the high-affinity complex by the beta chain (CD122) and gamma-c (CD132). The three-tier affinity transition underlies the bipolar nature of I
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Keywords: IL-2, IL-2R alpha, CD25, CD122, CD132, ternary complex, affinity
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