What Is Biotinylated CRBN/DDB1: How the Labeled Complex Serves PROTAC Degradation Research
Biotinylated CRBN/DDB1 is the substrate-recognition module of CRL4 E3 ligase, immobilized for binding assays. This article explains its role in PROTAC and molecular-glue studies.
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Keywords: Biotinylated CRBN/DDB1, CRL4, E3 ligase, PROTAC, molecular glue, TR-FRET, ternary complex, UA080262
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
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