Murine IFN-γ: How a Homodimer Drives Both Macrophage Activation and Growth Arrest
IFN-γ is a homodimeric type-II interferon engaging IFNGR1/IFNGR2 and JAK-STAT1. This article explains how one dimer activates macrophages and restrains proliferation at once.
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Abstract: IFN-γ is a homodimeric type-II interferon engaging IFNGR1/IFNGR2 and JAK-STAT1. This article explains how one dimer activates macrophages and restrains proliferation at once.
Keywords: IFN-gamma mouse, homodimer, IFNGR1, IFNGR2, STAT1, JAK, macrophage activation, UA040065
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
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