pH-Sensitive IgG Labeling: Why Fluorescence Only Lights Up After the Antibody Enters the Cell
pH-sensitive dyes stay quenched at neutral pH and brighten in acidic endosomes. This article explains the self-quenching principle, lysosomal pH and how labeled antibodies report internalization.
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Keywords: pH-sensitive IgG labeling reagent, pH-sensitive fluorescent probe, antibody internalization assay, internalization quantification, self-quenching, lysosomal pH, UA070122
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
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