What Is an MHC Tetramer and How It Detects Antigen-Specific T Cells
MHC tetramers directly stain antigen-specific T cells by multivalent TCR engagement. Using the classic H-2K(b)/SIINFEKL OVA tetramer, this article explains the principle, models and staining workflow.
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Keywords: MHC tetramer, antigen-specific T cell, SIINFEKL, OVA, H-2Kb, flow cytometry, UA089023
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
Disclaimer: This article partially utilizes artificial intelligence assistance in its creation. If any content involves copyright or intellectual property issues, please let us know and we promise to verify and remove it as soon as possible.
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