From Thymic Graduation to Peripheral Patrol: Three Stations in the Life of a CD8alpha-beta T Cell

The life of a CD8alpha-beta T cell resembles a long patrol: thymic graduation examination, peripheral surveillance and recognition, and response upon alarm. This article dissects the molecular role of the co-receptor at each of the three life stages.

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Abstract: The life of a CD8alpha-beta T cell resembles a long patrol: thymic graduation examination, peripheral surveillance and recognition, and response upon alarm. This article dissects the molecular role of the co-receptor at each of the three life stages.

Keywords: CD8 alpha beta, thymic positive selection, CD8 T cell, co-receptor, immunological synapse, effector T cell, UA016094

Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.

This article is reviewed and published by the technical expert team of UA

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