Two Keys to Open the Door: How CD8alpha-beta Cooperates with TCR to Read MHC-I in Three Relays
T cell recognition of target cells works like a two-key access system: TCR is the primary key and CD8alpha-beta is the gatekeeper confirmation. This article breaks down, in three relays, how the co-receptor converts weak and transient recognition int
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Keywords: CD8 alpha beta, TCR, MHC-I, co-receptor, Lck, immunological synapse, T cell activation, UA016095
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
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