CHI3L1: Signaling Mechanisms and Disease Spectrum of Chitinase-Like Protein 1
CHI3L1 (YKL-40) is a secreted glycoprotein of the glycoside hydrolase 18 family without enzymatic activity. This review covers its molecular features, receptor signaling network, attributes as a serum biomarker, and disease associations including ast
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Abstract: CHI3L1 (YKL-40) is a secreted glycoprotein of the glycoside hydrolase 18 family without enzymatic activity. This review covers its molecular features, receptor signaling network, attributes as a serum biomarker, and disease associations including asthma, liver fibrosis and cancer.
Keywords: CHI3L1, YKL-40, chitinase-like protein 1, IL-13R alpha 2, Syndecan-1, liver fibrosis, UA019077
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
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