ActRIIB: The Negative Regulator Switch of Muscle Growth and Its Research Landscape
ActRIIB is the type I receptor kinase for myostatin and activin signaling, writing the 'grow less muscle' instruction into the nucleus. This review covers its receptor structure, signaling axis, disease associations and in vitro research tools.
- Recent Advances
Keywords: ActRIIB,Myostatin,Activin,SMAD2/3,Muscle growth,Inhibitor screening,UA079045
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
Disclaimer: This article partially utilizes artificial intelligence assistance in its creation. If any content involves copyright or intellectual property issues, please let us know and we promise to verify and remove it as soon as possible.
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