A Door That Needs Two Keys: How FGF19, FGFR4 and KLB Open the Gate
The FGFR4 door opens only when both keys—FGF19 and KLB—are inserted at the same time. This article walks through the four-step assembly of the FGF19-FGFR4-KLB ternary complex and the full process of signal entry.
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Keywords: FGFR4,FGF19,Beta-Klotho,KLB,Ternary complex,Hepatocellular carcinoma,UA011375
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
This article is reviewed and published by the technical expert team of UA
Disclaimer: This article partially utilizes artificial intelligence assistance in its creation. If any content involves copyright or intellectual property issues, please let us know and we promise to verify and remove it as soon as possible.
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