NNMT: An Epigenetic Switch on the Nicotinamide Metabolic Branch
NNMT catalyzes nicotinamide and SAM into 1-MNA and SAH, connecting the NAD+ salvage pathway with methylation metabolism. This review covers its catalytic mechanism, epigenetic effects, disease associations and in vitro research essentials.
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Abstract: NNMT catalyzes nicotinamide and SAM into 1-MNA and SAH, connecting the NAD+ salvage pathway with methylation metabolism. This review covers its catalytic mechanism, epigenetic effects, disease associations and in vitro research essentials.
Keywords: NNMT,Nicotinamide N-methyltransferase,1-MNA,SAM,Epigenetics,Cancer metabolism,UA085039
Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.
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