TLR4: The First Sentinel of Innate Immunity and a Contested Target for Immunomodulatory Drugs

Once known merely as the LPS sensor, TLR4 now stands at the crossroads of adjuvant development, sepsis intervention and antitumor immunity. This article moves from the structural basis of ligand recognition to its translational value.

  • Recent Advances
Recent Advances
Abstract: Once known merely as the LPS sensor, TLR4 now stands at the crossroads of adjuvant development, sepsis intervention and antitumor immunity. This article moves from the structural basis of ligand recognition to its translational value.

Keywords: TLR4,MD-2,LPS recognition,Receptor dimerization,Innate immunity,UA01001C-28

Note: The full article is published in Chinese. Please refer to the Chinese version for complete experimental details, figures and product references. For product inquiries, visit www.ua-bio.com.

This article is reviewed and published by the technical expert team of UA

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