Technical Articles

skeletal muscle regulation

What is the GDF-8 target? Complete analysis of Myostatin molecular structure and signaling pathway

2026-06-30

Growth differentiation factor 8, abbreviated as GDF-8, commonly known as Myostatin in the industry, belongs to the TGF-β superfamily of secreted proteins. It is currently a core and highly popular target in the field of skeletal muscle regulation and was first identified in 1997 by a research team from a mouse skeletal muscle cDNA library.

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Metabolism
GDF-8
Myostatin
muscle growth inhibitor
GDF-8 target
TGF-β superfamily
skeletal muscle regulation
SMAD signaling pathway

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