Technical Articles

This article focuses on the technical principles of pH-sensitive IgG fluorescent labeling reagents, systematically elucidating their molecular mechanism of distinguishing cell surface-bound antibodies from internalized antibodies through pH-dependent fluorescence signal changes. It analyzes the application value of this technology in antibody-drug conjugate (ADC) screening and receptor internalization kinetics studies.

This article focuses on the technical principles of pH-sensitive IgG fluorescent labeling reagents, systematically elucidating the molecular mechanism by which they utilize pH-dependent fluorescence signal changes to monitor antibody internalization processes, and analyzing their application value in antibody-drug conjugate screening and internalization kinetics research.