Technical Articles

CD3εδ 异二聚体:TCR 复合物信号模块的结构与研究全景
CD3εδ Heterodimer: Structure and Research Landscape of the TCR Signal Module
发布时间 2026-09-21
The CD3εδ heterodimer pairs an ectodomain Ig fold with cytoplasmic ITAM motifs, forming the signaling core of the TCR complex. This review covers its biosynthesis and assembly order, interchain disulfide pairing, species considerations for mouse stud
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  • Immunity/Inflamma
  • CD3εδ heterodimer
  • TCR complex
  • ITAM
  • cross-species
  • mouse
NNMT 的跨物种图景:序列、表达与模型选择
The Cross-Species Landscape of NNMT: Sequence, Expression and Model Selection
发布时间 2026-09-20
From mouse to rhesus monkey, NNMT differs in sequence conservation, tissue expression profiles and model fit. This review covers the core dimensions of cross-species comparison and the logic of aligning tool proteins.
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  • Metabolism
  • NNMT
  • Cross-species
  • Sequence conservation
  • Tissue expression
  • Model selection
  • Mouse
  • Rhesus monkey
  • UA085036
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