Technical Articles

lysosomal pH

pH-Sensitive IgG Labeling: Why Fluorescence Only Lights Up After the Antibody Enters the Cell

2026-10-20

pH-sensitive dyes stay quenched at neutral pH and brighten in acidic endosomes. This article explains the self-quenching principle, lysosomal pH and how labeled antibodies report internalization.

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Drug Research
pH-sensitive IgG labeling reagent
pH-sensitive fluorescent probe
antibody internalization assay
internalization quantification
self-quenching
lysosomal pH
UA070122

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