Technical Articles

一根免疫导线:TCE 双抗借 CD3εγ 接通杀伤电路的全过程
An Immunological Wire: How T-Cell Engagers Connect the Killing Circuit through CD3 epsilon-gamma
发布时间 2026-09-23
A T-cell engager works like a wire: one end plugs into a tumor antigen, the other into CD3 epsilon-gamma. This article dissects immunological synapse formation, the ITAM phosphorylation cascade and the affinity safety valve across a four-step workflo
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  • Immunity/Inflamma
  • CD3epsilon-gamma
  • T-cell engager
  • immunological synapse
  • ITAM
  • affinity tuning
  • UA016084
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