Technical Articles
immunological synapse
An Immunological Wire: How T-Cell Engagers Connect the Killing Circuit through CD3 epsilon-gamma
A T-cell engager works like a wire: one end plugs into a tumor antigen, the other into CD3 epsilon-gamma. This article dissects immunological synapse formation, the ITAM phosphorylation cascade and the affinity safety valve across a four-step workflo
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- Immunity/Inflamma
- CD3epsilon-gamma
- T-cell engager
- immunological synapse
- ITAM
- affinity tuning
- UA016084
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