Technical Articles
costimulation
Recombinant Human CD40 Fc Chimera: How the Immune Switch Is Opened at the Molecular Level
2026-10-16CD40 is a TNF receptor family costimulatory molecule on B cells and dendritic cells. This article explains its trimerization-driven signaling, CD40L engagement and why the Fc chimera format is the standard reagent for binding studies.
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- Immunity/Inflamma
- CD40
- TNFRSF5
- CD40L
- Fc chimera
- costimulation
- B cell
- dendritic cell
- TRAF
- UA010194
- 1
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