Technical Articles
combination therapy
Clinical Setbacks of IGF1R Antibodies: From Figitumumab Monotherapy to a Combination-Treatment Paradigm Shift
After figitumumab monotherapy failed, the IGF1R antibody field shifted toward combination treatment and biomarker stratification. This article traces the paradigm shift in IGF1R translational research and its in vitro tool support.
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- Cancer
- IGF1R antibodies
- figitumumab
- ganitumab
- combination therapy
- biomarkers
- tumor targeting
- UA016082
- alpha2beta2
- 1







