Technical Articles

This article breaks down the molecular events of CHI3L1 in tissue repair and the tumor microenvironment in four steps: alarm signaling, matrix remodeling, immune polarization toward Th2 responses, and angiogenesis.

The Vascular Endothelial Growth Factor (VEGF) signaling pathway is a key signaling network that regulates angiogenesis and vasculogenesis.

Vascular endothelial growth factor 165 (VEGF165) is the major functional isoform of VEGF-A. As the "master regulator" of angiogenesis, it plays a central role in tissue development, repair, and the pathogenesis of numerous major diseases.

VEGF165 is the predominant isoform of vascular endothelial growth factor-A, hailed as the "master switch" of angiogenesis. It plays a central role in development, repair, and numerous disease processes by precisely regulating the formation of new blood vessels.