Technical Articles

activin receptor 2A

ACVR2A (ActRIIA): Signaling Mechanisms and Ligand Network of a TGF-beta Superfamily Type II Receptor

2026-09-29

ACVR2A (ActRIIA) is a type II serine/threonine kinase receptor of the TGF-beta superfamily. This review covers its molecular features, the activin/myostatin ligand network, SMAD2/3 signaling cascades, and key points in tumor and muscle research.

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Signaling Pathway
ACVR2A
ActRIIA
activin receptor 2A
TGF-beta superfamily
myostatin
SMAD2/3
UA085066

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