Technical Articles

This article systematically elaborates on the molecular characteristics and biological functions of VEGF165, a major isoform of vascular endothelial growth factor, highlighting its pivotal role as a key regulator of angiogenesis in the development and progression of solid tumors. It also analyzes its clinical application value in broad-spectrum tumor screening, efficacy evaluation, and prognosis monitoring.

Vascular endothelial growth factor 165 (VEGF165) is the major functional isoform of VEGF-A. As the "master regulator" of angiogenesis, it plays a central role in tissue development, repair, and the pathogenesis of numerous major diseases.