Technical Articles
UA089023
How to Choose an MHC Tetramer: Allele, PE/APC Label and Selection Guide
2026-10-10A selection guide for MHC tetramers: how to match MHC allele and peptide, choose PE vs. APC labels for multicolor flow, and avoid common pitfalls in T-cell staining.
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- Immunity/Inflamma
- MHC tetramer selection
- allele matching
- PE
- APC
- multicolor flow
- tetramer guide
- UA089023
What Is an MHC Tetramer and How It Detects Antigen-Specific T Cells
2026-10-10MHC tetramers directly stain antigen-specific T cells by multivalent TCR engagement. Using the classic H-2K(b)/SIINFEKL OVA tetramer, this article explains the principle, models and staining workflow.
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- Immunity/Inflamma
- MHC tetramer
- antigen-specific T cell
- SIINFEKL
- OVA
- H-2Kb
- flow cytometry
- UA089023
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