Technical Articles

NNMT 的跨物种图景:序列、表达与模型选择
The Cross-Species Landscape of NNMT: Sequence, Expression and Model Selection
发布时间 2026-09-20
From mouse to rhesus monkey, NNMT differs in sequence conservation, tissue expression profiles and model fit. This review covers the core dimensions of cross-species comparison and the logic of aligning tool proteins.
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  • Metabolism
  • NNMT
  • Cross-species
  • Sequence conservation
  • Tissue expression
  • Model selection
  • Mouse
  • Rhesus monkey
  • UA085036
一枚甲基团的账本:NNMT 如何改写细胞的甲基化容量
The Ledger of a Single Methyl Group: How NNMT Rewrites Cellular Methylation Capacity
发布时间 2026-09-20
Picture the NNMT reaction as an accounting exercise: SAM is the wallet, SAH the IOU, and histone methylation is where the money is spent. This article walks through the bookkeeping and reconciliation of this methyl ledger in four steps.
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  • Metabolism
  • NNMT
  • SAM
  • SAH
  • Histone methylation
  • Epigenetics
  • Metabolite quantification
  • UA085036
猴源 NNMT 研究工具:非人灵长类实验的序列与功能对齐
Monkey-Derived NNMT Research Tools: Sequence and Functional Alignment for Non-Human Primate Studies
发布时间 2026-09-20
A tool-oriented guide to non-human primate NNMT research: three layers of alignment—sequence identity verification, kinetic parallel testing and antibody cross-reactivity validation—plus QC interpretation of recombinant rhesus NNMT.
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  • Metabolism
  • NNMT
  • Rhesus macaque
  • Non-human primate
  • Cross-species
  • Sequence identity
  • Activity assay
  • UA085036
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