Technical Articles
UA085036
The Cross-Species Landscape of NNMT: Sequence, Expression and Model Selection
From mouse to rhesus monkey, NNMT differs in sequence conservation, tissue expression profiles and model fit. This review covers the core dimensions of cross-species comparison and the logic of aligning tool proteins.
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- Metabolism
- NNMT
- Cross-species
- Sequence conservation
- Tissue expression
- Model selection
- Mouse
- Rhesus monkey
- UA085036
The Ledger of a Single Methyl Group: How NNMT Rewrites Cellular Methylation Capacity
Picture the NNMT reaction as an accounting exercise: SAM is the wallet, SAH the IOU, and histone methylation is where the money is spent. This article walks through the bookkeeping and reconciliation of this methyl ledger in four steps.
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- Metabolism
- NNMT
- SAM
- SAH
- Histone methylation
- Epigenetics
- Metabolite quantification
- UA085036
Monkey-Derived NNMT Research Tools: Sequence and Functional Alignment for Non-Human Primate Studies
A tool-oriented guide to non-human primate NNMT research: three layers of alignment—sequence identity verification, kinetic parallel testing and antibody cross-reactivity validation—plus QC interpretation of recombinant rhesus NNMT.
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- Metabolism
- NNMT
- Rhesus macaque
- Non-human primate
- Cross-species
- Sequence identity
- Activity assay
- UA085036
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