Technical Articles
UA040180
DKK-1 Selection: Price, Vendors and an Activity-Definition-First Checklist
A selection checklist for recombinant human DKK-1: how activity is defined, purity and endotoxin indicators, and the vendor questions to ask before comparing prices.
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- Signaling Pathway
- DKK-1 selection
- activity definition
- price
- vendor
- purity
- Wnt assay
- UA040180
What Is DKK-1: Why DKK-1 Is the Brake of Wnt Signaling
DKK-1 binds LRP5/6 and Kremen to block Wnt signaling. This article explains the brake mechanism, bone and cancer contexts and how recombinant DKK-1 supports Wnt studies.
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- Signaling Pathway
- DKK-1
- Wnt signaling
- LRP5/6
- Kremen
- bone metabolism
- cancer
- UA040180
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