Technical Articles

UA040065

Where Murine IFN-γ Sits in the Industry: From Immunology Reagents to Cell-Therapy Readouts

2026-10-26

IFN-γ links Th1 biology, release testing and cell-therapy potency readouts. This article maps the industry chain and the consistency expectations reagent suppliers must meet.

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Immunity/Inflamma
IFN-gamma industry
Th1 response
cell therapy
cytokine release
lot release
consistency
UA040065

Working with Murine IFN-γ: Reconstitution, Dosing Gradients and Four Readouts in Order

2026-10-26

A step-ordered practical guide: reconstitution and aliquoting, dose-gradient design, and four readouts from STAT1 phosphorylation to nitrite-based macrophage activation assays.

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Immunity/Inflamma
IFN-gamma usage
reconstitution
dosing gradient
STAT1 phosphorylation
Griess assay
UA040065

Murine IFN-γ: How a Homodimer Drives Both Macrophage Activation and Growth Arrest

2026-10-26

IFN-γ is a homodimeric type-II interferon engaging IFNGR1/IFNGR2 and JAK-STAT1. This article explains how one dimer activates macrophages and restrains proliferation at once.

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Immunity/Inflamma
IFN-gamma mouse
homodimer
IFNGR1
IFNGR2
STAT1
JAK
macrophage activation
UA040065

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