Technical Articles

This article breaks down stress granule assembly and mRNA translation regulation in four steps - mRNA storage, stress signaling, granule assembly and clearance - centered on the regulatory role of Caprin-1 and its interplay with G3BP1, autophagy and

The key challenges of Caprin-1 binding assays are sequence alignment across three species and interpretation of anomalous migration. This article reviews QC evidence of CHO-expressed Caprin-1, ELISA EC50 benchmarks, SPR/BLI parameters and the logic o

Caprin-1 is both a cytosolic RNA-binding protein of stress granules and a membrane-expressed pan-cancer target. This article follows the translational storyline through its disease spectrum, miRNA regulation and the clinical development of TRK-950 fr