Technical Articles
UA016100
The Plectin Interaction Network: A Systematic Review from Domains to Detection Platforms
Plectin's interaction network is dominated by dynamic, weak-binding cytoskeletal partners. This review systematically covers its interactors, the boundaries of four detection platforms, parameter settings and sources of false positives, providing a p
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- Cell Biology
- Plectin assay
- Co-immunoprecipitation
- GST pull-down
- BioID
- Interacting proteins
- UA016100
A Force Transmission Chain: The Pivotal Role of Plectin in Mechanotransduction
Mechanical forces travel from the extracellular matrix through integrin–focal adhesion complexes and the Plectin-bridged cytoskeletal network, ultimately shaping YAP/TAZ transcriptional responses. This article breaks down each segment of the chain an
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- Cell Biology
- Plectin
- Mechanotransduction
- Focal adhesion
- YAP TAZ
- Matrix stiffness
- UA016100
Human Plectin Research Tools: Aligning Splice Variants, Localization and Antibodies
Human Plectin is a family of variants generated by alternative splicing. From a tool perspective, this article maps the variant-to-localization relationships, sources of antibody epitope misjudgment and record-keeping standards, helping researchers k
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- Cell Biology
- Plectin
- Splice variant
- Subcellular localization
- Hemidesmosome
- Antibody selection
- UA016100
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