Technical Articles

Plectin 互作网络:从结构域到检测平台的系统综述
The Plectin Interaction Network: A Systematic Review from Domains to Detection Platforms
发布时间 2026-09-20
Plectin's interaction network is dominated by dynamic, weak-binding cytoskeletal partners. This review systematically covers its interactors, the boundaries of four detection platforms, parameter settings and sources of false positives, providing a p
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  • Cell Biology
  • Plectin assay
  • Co-immunoprecipitation
  • GST pull-down
  • BioID
  • Interacting proteins
  • UA016100
一条力的传递链:Plectin 在机械力转导中的枢纽角色
A Force Transmission Chain: The Pivotal Role of Plectin in Mechanotransduction
发布时间 2026-09-20
Mechanical forces travel from the extracellular matrix through integrin–focal adhesion complexes and the Plectin-bridged cytoskeletal network, ultimately shaping YAP/TAZ transcriptional responses. This article breaks down each segment of the chain an
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  • Cell Biology
  • Plectin
  • Mechanotransduction
  • Focal adhesion
  • YAP TAZ
  • Matrix stiffness
  • UA016100
人源 Plectin 研究工具:剪接变体、定位与抗体的对齐方法
Human Plectin Research Tools: Aligning Splice Variants, Localization and Antibodies
发布时间 2026-09-20
Human Plectin is a family of variants generated by alternative splicing. From a tool perspective, this article maps the variant-to-localization relationships, sources of antibody epitope misjudgment and record-keeping standards, helping researchers k
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  • Cell Biology
  • Plectin
  • Splice variant
  • Subcellular localization
  • Hemidesmosome
  • Antibody selection
  • UA016100
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