Technical Articles

The human CD8alpha-beta heterodimer is the co-receptor of cytotoxic T cells. This review covers its molecular features, parameter comparison between human and cynomolgus monkey tools, site-specific biotinylation design, and key points of immune evalu

The life of a CD8alpha-beta T cell resembles a long patrol: thymic graduation examination, peripheral surveillance and recognition, and response upon alarm. This article dissects the molecular role of the co-receptor at each of the three life stages.

From HIV progression markers to tumor-infiltrating lymphocyte density, and further to immunotherapy response evaluation, this article follows the industry narrative to dissect how human CD8alpha-beta became a common yardstick for effector T cell rese