Technical Articles

UA011246

Alexa Fluor 647荧光标记人BCMA蛋白：BCMA 这条 CAR-T 路线，为什么在多发性骨髓瘤里站住了？

BCMA as a CAR-T Route: Why It Has Held Its Ground in Multiple Myeloma

2026-10-20

This article reviews the BCMA CAR-T route in multiple myeloma: target biology, dual-epitope strategies and why release testing of BCMA-directed constructs depends on reliable target detection reagents.

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Cancer
BCMA CAR-T
multiple myeloma
TNFRSF17
dual epitope
target detection
release testing
UA011246

Alexa Fluor 647荧光标记人BCMA蛋白：CAR 阳性率测不准，染色与对照该怎么设？

Alexa Fluor 647-Labeled BCMA: Staining and Control Design When CAR Positive Rates Look Unreliable

2026-10-20

A practical guide to CAR positive-rate staining with directly labeled BCMA: control design, competition experiments, compensation setup and gating strategy for reproducible flow cytometry readouts.

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Cancer
CAR positive rate
flow cytometry controls
isotype control
competition assay
compensation setup
gating strategy
UA011246

Alexa Fluor 647荧光标记人BCMA蛋白：CAR 表达检测为什么可以直接读荧光？

Alexa Fluor 647-Labeled BCMA: Why CAR Expression Detection Can Read Fluorescence Directly

2026-10-20

Directly labeled BCMA protein with Alexa Fluor 647 enables one-step flow cytometric detection of CAR expression. This article explains why the dye reads directly and how conjugation quality shapes the signal.

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Cancer
BCMA
TNFRSF17
CD269
Alexa Fluor 647
CAR expression detection
flow cytometry staining
direct labeling
UA011246

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