Technical Articles

UA010382

重组人il-4r alpha/cd124蛋白：一个共用亚基，怎么撑起一串适应症？

One Shared Subunit, Many Indications: How IL-4R alpha Anchors a Drug Pipeline

2026-10-21

This article reviews how IL-4R alpha supports a string of indications from atopic dermatitis to asthma and COPD, and why target biology keeps it central in biologic pipelines.

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Immunity/Inflamma
IL-4R alpha
dupilumab
atopic dermatitis
asthma
Th2 inflammation
biologic pipeline
UA010382

重组人il-4r alpha/cd124蛋白做结合实验，曲线起不来通常卡在哪几步？

IL-4R alpha Binding Assays: Where Flat Curves Usually Come From

2026-10-21

A troubleshooting guide for IL-4R alpha binding experiments: receptor orientation, ligand pairing, coating format and control design when binding curves stay flat or fail to reach plateau.

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Immunity/Inflamma
binding assay
IL-4R alpha
CD124
ELISA
receptor-ligand pairing
control design
signal troubleshooting
UA010382

重组人il-4r alpha/cd124蛋白：一个亚基，怎么同时接住 IL-4 和 IL-13？

IL-4R alpha/CD124: How One Shared Subunit Serves Both IL-4 and IL-13

2026-10-21

IL-4R alpha (CD124) is the common subunit of the type I and type II IL-4 receptor complexes. This article explains how one receptor chain accommodates both IL-4 and IL-13 signaling.

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Immunity/Inflamma
IL-4R alpha
CD124
IL-4
IL-13
type II receptor
STAT6
Th2
receptor complex
UA010382

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