Technical Articles
Tumor immune evasion
DcR3: From Driver of Tumor Immune Evasion to Inflammation Brake—Translational Prospects of a Two-Faced Target
DcR3 promotes immune escape in the tumor microenvironment while acting as inhibitory feedback in chronic inflammation. This article reviews its bidirectional mechanisms, sources of expression regulation, variable-control essentials on both research f
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- Immunity/Inflamma
- DcR3
- Tumor immune evasion
- Chronic inflammation
- Immunosuppression
- Biomarker
- UA019076
The Immune System's Decoy Keys: How DcR3 Intercepts Three Death Signals
As a soluble decoy receptor, DcR3 intercepts FasL, LIGHT and TL1A one after another. Following the process of ligand departure, key swap and signal shutdown, this article dissects the decoy mechanism and the logic of its experimental validation.
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- Immunity/Inflamma
- DcR3
- Decoy receptor
- FasL
- LIGHT
- TL1A
- Tumor immune evasion
- UA019076
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