Technical Articles

Growth differentiation factor 8, abbreviated as GDF-8, commonly known as Myostatin in the industry, belongs to the TGF-β superfamily of secreted proteins. It is currently a core and highly popular target in the field of skeletal muscle regulation and was first identified in 1997 by a research team from a mouse skeletal muscle cDNA library.

Activin A, a key member of the TGF-β superfamily, is a dimeric protein formed by two βA subunits linked via disulfide bonds. This critical signaling molecule plays a central role in physiological processes such as embryonic development, tissue repair, and immune regulation, but its dysregulation has also become a pivotal factor in the pathogenesis of various diseases.

Activin A is a secreted protein belonging to the transforming growth factor-β superfamily. Like other well-known family members such as TGF-β and BMPs, it plays a central role in cell growth, differentiation, and apoptosis.