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TCR
四棒接力：CD3εδ 如何把抗原识别转成 T 细胞激活
A Four-Leg Relay: How CD3εδ Translates Antigen Recognition into T Cell Activation
发布时间 2026-09-21
T cell activation is a relay race: TCR-alpha/beta binds the pMHC, CD3εδ and CD3εγ transmit the conformational change across the membrane, CD3ζζ converts it into ITAM phosphorylation, and ZAP-70 takes the final leg. This article walks through each bat
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  • Immunity/Inflamma
  • CD3
  • CD3εδ heterodimer
  • TCR
  • ITAM
  • ZAP-70
  • T cell activation
Total 1
  • 1
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