Technical Articles
TAM
M-CSF in Drug Development: The CSF1R Gateway to the Immune Microenvironment
2026-10-14CSF1R inhibitors opened macrophage-focused immunotherapy strategies. This article reviews CSF1R-directed approaches, tumor-associated macrophages and how recombinant mouse M-CSF supports translational research.
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- Immunity/Inflamma
- M-CSF
- CSF1R
- TAM
- immune microenvironment
- osteoclast
- combination therapy
- translational research
- UA040128
Recombinant Mouse M-CSF: Driving Monocytes to Macrophages via CSF1R
2026-10-14Mouse M-CSF (CSF1) binds CSF1R to drive monocyte survival, proliferation and differentiation into macrophages. This article explains the CSF1/CSF1R axis, BMDM generation and osteoclast biology.
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- Immunity/Inflamma
- M-CSF
- CSF1
- CSF1R
- macrophage
- monocyte
- BMDM
- osteoclast
- TAM
- UA040128
- 1
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