Technical Articles

T-cell engager
TCE 双抗的 CD3 臂：为什么研发都从异二聚体蛋白开始
The CD3 Arm of T-Cell Engagers: Why Development Starts with Heterodimeric Proteins
发布时间 2026-09-20
The same CD3 arm can be precision guidance or a cytokine storm. Along the design challenges of T-cell engagers, this article dissects why the CD3εγ heterodimer has become the standard starting tool for bispecific antibody development.
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  • Immunity/Inflamma
  • CD3
  • CD3epsilon-gamma heterodimer
  • T-cell engager
  • Affinity tuning
  • Cytokine release
  • UA016046
Total 1
  • 1
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