Technical Articles

T cell activation is a relay race: TCR-alpha/beta binds the pMHC, CD3εδ and CD3εγ transmit the conformational change across the membrane, CD3ζζ converts it into ITAM phosphorylation, and ZAP-70 takes the final leg. This article walks through each bat

T lymphocytes, as the core cells of adaptive immune responses, play an irreplaceable role in anti-infection, anti-tumor, and immune regulation.

T lymphocytes are the core executors of the human adaptive immune system, playing a critical role in anti-infection and anti-tumor immune responses.