Technical Articles

Fibroblast growth factors are a family of structurally related polypeptides that include at least eighteen members, widely involved in various physiological and pathological processes such as cell growth, differentiation, angiogenesis, tissue repair, and tumorigenesis.

Growth factors are a class of polypeptides that regulate cell growth and various other biological functions by binding to specific, high-affinity receptors on the cell membrane. In academic literature, they are often referred to as "growth peptides." These molecules are widely distributed in various tissues of the body, including developing embryonic tissues and differentiated mature tissues.

Glycogen is the primary storage form of glucose in living organisms, widely present in the liver, skeletal muscles, and various cell types. As a key molecule in cellular energy metabolism, the synthesis, storage, and breakdown of glycogen directly reflect the energy status and metabolic activity of cells. In fields such as metabolic biology, cell physiology, and drug discovery, the accurate quantification of glycogen content is one of the core indicators for assessing cellular metabolic states and the effects of compound interventions.

Autoimmune diseases represent the second largest therapeutic area globally, with the core logic of drug development undergoing profound changes: TNF-α inhibitors pioneered targeted therapy for autoimmune conditions, but what truly drives the market's structural boom is the IL-23/IL-17A signaling axis and its associated Th17 pathway.

ITK is a core non-receptor tyrosine kinase in the T cell receptor signaling pathway, playing a regulatory role in T cell subset differentiation by controlling PLCγ1 activation and calcium signal intensity.

Alexa Fluor 647-labeled GPC3 Fc chimeric protein (abbreviated as AF647-GPC3-Fc) is currently the mainstream high-precision fluorescent probe reagent in the fields of liver cancer-targeted research, cell surface marker detection, and protein interaction analysis.

Receptor tyrosine kinase-like orphan receptor 1 is a member of the ROR receptor family, which includes two closely related type I transmembrane proteins, ROR1 and ROR2. The extracellular domain of ROR1 contains an immunoglobulin-like domain, a cysteine-rich domain, and a Kringle domain.

The MSLN gene encodes a precursor protein that undergoes proteolytic processing to generate two protein products: megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor acts as a cytokine that stimulates the formation of megakaryocyte colonies in the bone marrow.

Guanylyl cyclase C, also known as GUC2C or STAR, is a guanylyl cyclase that catalyzes the synthesis of cyclic GMP from GTP. It plays a key role in regulating intestinal homeostasis and is central to intestinal health and colorectal cancer development, making it a highly promising therapeutic target.

Osteoarthritis is a common degenerative joint disease characterized by pathological features such as joint cartilage degeneration, subchondral bone sclerosis, and synovial inflammation.