Technical Articles
SAH
The Ledger of a Single Methyl Group: How NNMT Rewrites Cellular Methylation Capacity
2026-09-20Picture the NNMT reaction as an accounting exercise: SAM is the wallet, SAH the IOU, and histone methylation is where the money is spent. This article walks through the bookkeeping and reconciliation of this methyl ledger in four steps.
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- Metabolism
- NNMT
- SAM
- SAH
- Histone methylation
- Epigenetics
- Metabolite quantification
- UA085036
NNMT Activity Assay Tools: Enzyme Reaction Systems, Platform Selection and Data Interpretation
2026-09-20A tool-oriented guide to NNMT activity assays: SAM stability management, interference control of SAH product inhibition, platform selection between luminescent coupling and LC-MS, and interpretation paths for three common data anomalies.
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- Metabolism
- NNMT assay
- Enzyme kinetics
- SAM
- SAH
- Luminescent coupling
- LC-MS
- UA085039
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