Technical Articles
PRLR
One Receptor, Two Narratives: Why PRLR Has Returned to the Targeting Spotlight
2026-09-22Once defined by lactation biology, the prolactin receptor PRLR has re-entered targeted research three decades later on the strength of high expression profiles in luminal breast cancer. This article unpacks the receptor's dual identity and translatio
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- Metabolism
- PRLR
- prolactin receptor
- breast cancer
- STAT5
- antagonist
- target research
PRLR: Structural Isoforms, JAK2-STAT5 Signaling and the Research Landscape of the Prolactin Receptor
2026-09-22A systematic review of the prolactin receptor (PRLR), a class I cytokine receptor family member that transmits prolactin signals via the JAK2-STAT5 pathway: receptor structure and isoforms, signaling hierarchy, physiological functions, and the toolki
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- Metabolism
- PRLR
- prolactin receptor
- JAK2
- STAT5
- breast cancer
- recombinant protein
From Endometriosis to Androgenetic Alopecia: How the PRLR Target Ushers in a New Era of Differentiated Antibody Therapy
2026-05-20PRLR is a transmembrane protein belonging to the type I cytokine receptor family, and its endogenous ligand prolactin (PRL) plays extensive roles in reproduction, immunity, and metabolism.
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- Cancer
- PRLR
- prolactin receptor
- endometriosis
- androgenetic alopecia
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