Technical Articles
Nicotinamide N-methyltransferase
NNMT: An Epigenetic Switch on the Nicotinamide Metabolic Branch
NNMT catalyzes nicotinamide and SAM into 1-MNA and SAH, connecting the NAD+ salvage pathway with methylation metabolism. This review covers its catalytic mechanism, epigenetic effects, disease associations and in vitro research essentials.
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- Metabolism
- NNMT
- Nicotinamide N-methyltransferase
- 1-MNA
- SAM
- Epigenetics
- Cancer metabolism
- UA085039
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