Technical Articles

This article focuses on the molecular characteristics and biological functions of neuregulin 1 (NRG1), systematically elaborating its molecular mechanism as a member of the epidermal growth factor family in mediating cell signal transduction through ErbB receptor tyrosine kinases, analyzing the dual role of NRG1 in peripheral nervous system development, nerve repair, and epithelial-derived tumorigenesis, and exploring the clinical significance of NRG1 gene fusion as a carcinogenic driver and its detection strategies.