Technical Articles

AFM13 bridges CD30-positive lymphoma cells to NK-cell CD16a. This article explains the tetravalent bispecific architecture and NK-cell engagement readouts.

Natural killer cells (NK cells) are the third major type of lymphocytes, apart from T cells and B cells. They can spontaneously recognize abnormal cells in the body, rapidly eliminate them through cytotoxic effects, and produce various pro-inflammatory factors and chemokines to recruit and activate other immune cells, thereby initiating adaptive immune responses.