Technical Articles

TLR4/MD-2 信号通路:配体识别、双分支转导与研究全景
The TLR4/MD-2 Signaling Pathway: Ligand Recognition, Dual-Branch Transduction and Research Landscape
发布时间 2026-09-20
TLR4 signaling branches at the TIR domain into MyD88-dependent and TRIF-dependent pathways, driving NF-κB/MAPK and IRF3/interferon responses respectively. This review systematically covers pathway hierarchy, readout indicators and experimental consid
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  • Immunity/Inflamma
  • TLR4
  • MyD88
  • TRIF
  • NF-κB
  • IRF3
  • Signaling pathway
  • UA01001C-28
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