Technical Articles

ActRIIB:肌肉生长的负调控开关与研究全景
ActRIIB: The Negative Regulator Switch of Muscle Growth and Its Research Landscape
发布时间 2026-09-20
ActRIIB is the type I receptor kinase for myostatin and activin signaling, writing the 'grow less muscle' instruction into the nucleus. This review covers its receptor structure, signaling axis, disease associations and in vitro research tools.
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  • Signaling Pathway
  • ActRIIB
  • Myostatin
  • Activin
  • SMAD2/3
  • Muscle growth
  • Inhibitor screening
  • UA079045
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