Technical Articles
Muscle growth
ActRIIB: The Negative Regulator Switch of Muscle Growth and Its Research Landscape
ActRIIB is the type I receptor kinase for myostatin and activin signaling, writing the 'grow less muscle' instruction into the nucleus. This review covers its receptor structure, signaling axis, disease associations and in vitro research tools.
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- Signaling Pathway
- ActRIIB
- Myostatin
- Activin
- SMAD2/3
- Muscle growth
- Inhibitor screening
- UA079045
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