Technical Articles

The Nipah virus, as a highly lethal zoonotic pathogen, relies critically on its glycoprotein G for invading host cells, playing an irreplaceable role in this process. In-depth research into the structure and function of the G protein not only helps elucidate the virus's pathogenic mechanisms but also provides a vital molecular target for vaccine development and antiviral drug design. Recombinant G protein and its derivatives serve as essential research tools, demonstrating broad application prospects in virology studies and the development of immunodetection technologies.

High-Throughput AMP-Related Enzyme Target Drug Screening Technology UA-Glo® AMP Assay Kit

Interleukin-1 (IL-1) family is the core cytokine group regulating inflammatory response in the innate immune system. Its members participate in a variety of pathophysiological processes by binding specific receptor complexes. According to receptor binding characteristics, the IL-1 family can be divided into three subfamilies: IL-1, IL-18, and IL-36. Among them, the key co receptor IL-1R5 (i.e. IL-18R α) of the IL-18 subfamily plays an important role in infections, autoimmune diseases, and metabolic disorders.

The NS1 protein of dengue virus is the key to its pathogenesis, and the discovery of 2B7 antibodies provides new hope for blocking the destructive effect of this protein. This study not only deepens our understanding of the pathogenic mechanism of dengue virus, but also opens up new avenues for the development of more effective therapeutic drugs and vaccines.