Technical Articles
Membrane protein drug targets
Membrane Protein Drug Targets: Challenges in Structure Prediction and Opportunities for Therapeutic Development
This article focuses on the central role of membrane proteins as drug targets, systematically elaborating on the proportion of membrane proteins encoded in the human genome and their significant value as drug targets. It analyzes the critical role of inter-chain residue-residue contact information in predicting the structures of membrane protein complexes and discusses the technical challenges posed by the limited number of transmembrane proteins in contact prediction.
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- Drug Research
- Membrane protein drug targets
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