Technical Articles

This article systematically elucidates the physiological role of myelin basic protein (MBP) as a central nervous system-specific protein in maintaining myelin structural stability, and analyzes its clinical application value as a sensitive indicator and objective biochemical marker for brain injury in diseases such as acute traumatic brain injury, cerebral infarction, cerebral hemorrhage, and multiple sclerosis.

MBP (68-86) is the highly immunogenic core peptide segment of myelin basic protein, serving as the most representative autoantigen in the central nervous system and playing a critical role in the development and progression of demyelinating diseases such as multiple sclerosis.